SCHEMBL1021538

SCHEMBL1021538

CCCCCCCc1ccc(C(=O)Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ THRA P10827 9/20 0.70
▸ THRB P10828 9/20 0.70
▸ RARB P10826 5/20 0.65
▸ MEN1 O00255 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ ALDH1A1 P00352 1/20 0.65
▸ RARA P10276 1/20 0.65
▸ MAPT P10636 1/20 0.65
▸ MTOR P42345 1/20 0.65
▸ PLA2G1B P04054 3/20 0.59
▸ ATG4B Q9Y4P1 3/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385561 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1020543 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL17272985 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL269399 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8960387 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL2180222 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL9431010 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8728345 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1021352 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL158152 0.98 THRA (0.67) THRATHRBRARBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113403840-A Acyl chloride grafted cellulose fabric with lasting hydrophobicity and wear resistance, and preparation and application thereof 中科检测技术服务(广州)股份有限公司 2021-09-17 — — CN claimed
US-8703194-B2 Stimulus-responsive biodegradable polymers and methods of preparation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-04-22 — — US claimed
US-8658209-B2 — — 2014-02-25 — — US claimed
US-20090123544-A1 STIMULUS-RESPONSIVE BIODEGRADABLE POLYMERS AND METHODS OF PREPARATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2009-05-14 — — US claimed
CN-118027395-B Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2025-04-29 — — CN disclosed
CN-118027395-A Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2024-05-14 — — CN disclosed
US-20230416517-A1 TRANSPARENT AND ANTIBACTERIAL ORGANIC GLASS AND MANUFACTURING METHOD THEREFOR Zhejiang Huashuaite New Material Technology Co., Ltd. (CN) 2023-12-28 — — US disclosed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 — — US disclosed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 — — US disclosed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 — — US disclosed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 — — US disclosed
WO-2022252794-A1 TRANSPARENT AND ANTIBACTERIAL ORGANIC GLASS AND MANUFACTURING METHOD THEREFOR 浙江华帅特新材料科技有限公司 2022-12-08 — — WO disclosed
EP-0072863-A1 LIGHT MODULATOR, DEMODULATOR AND METHOD OF COMMUNICATION EMPLOYING THE SAME FERGASON, James L. (US) 1983-03-02 — — EP disclosed
WO-1982002960-A1 LIGHT MODULATOR,DEMODULATOR AND METHOD OF COMMUNICATION EMPLOYING THE SAME FERGASON JAMES L 1982-09-02 — — WO disclosed
US-4308162-A Novel yellow azo dyes and dichroic liquid crystal compositions made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 — — US disclosed
US-4308161-A FOR UPGRADING BLACK COLOR OF BLACK LIQUID CRYSTAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1981-12-29 — — US disclosed
US-4308164-A Novel yellow azo dyes and dichroic liquid crystal composition made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 — — US disclosed
US-4308163-A IMPROVING BLACK COLOR OF DICHROIC DYES GENERAL ELECTRIC COMPANY (US) 1981-12-29 — — US disclosed
US-4058478-A P-ALKYLBENZOIC ACID P'-CYANOPHENYL ESTER HOFFMANN-LA ROCHE INC. (US) 1977-11-15 — — US disclosed
US-3963311-A Liquid crystal esters HOFFMANN-LA ROCHE INC. (US) 1976-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123544-A1 STIMULUS-RESPONSIVE BIODEGRADABLE POLYMERS AND METHODS OF PREPARATION PAM, ATF4, MYD88 THRA 1237/4885THRB 1555/4885RARB 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback