Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 4/20 | 0.47 |
| ▸ | DHCR7 | Q9UBM7 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL640993 | 0.99 | EBP (0.47) | EBPDHCR7NPSR1ALDH1A1HTR7 | |
| SCHEMBL10205644 | 0.97 | EBP (0.48) | EBPDHCR7NPSR1ALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL640498 | 0.96 | EBP (0.47) | EBPDHCR7NPSR1ALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL640497 | 0.96 | EBP (0.47) | EBPDHCR7NPSR1ALDH1A1HTR7 | |
| SCHEMBL640983 | 0.88 | BDKRB1 (0.44) | EBPDHCR7ALDH1A1HTR7NPC1 | |
| SCHEMBL641104 | 0.88 | BDKRB1 (0.44) | EBPDHCR7ALDH1A1HTR7NPC1 | |
| SCHEMBL640984 | 0.88 | BDKRB1 (0.44) | EBPDHCR7ALDH1A1HTR7NPC1 | |
| SCHEMBL640597 | 0.87 | HTR6 (0.37) | EBPDHCR7ALDH1A1HTR7HTR1A | |
| SCHEMBL639575 | 0.85 | BDKRB1 (0.43) | EBPDHCR7ALDH1A1HTR7TP53 | |
| SCHEMBL639411 | 0.84 | HTR7 (0.39) | EBPDHCR7ALDH1A1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | EBP 2904/4885DHCR7 1725/4885NPSR1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.