Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967067 | 0.86 | CYP3A4 (0.44) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL10968171 | 0.86 | CYP3A4 (0.48) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL11535287 | 0.85 | CYP3A4 (0.42) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL8715405 | 0.82 | CYP3A4 (0.40) | TDP1PTPRZ1PTPN1CYP3A4TSHR | |
| SCHEMBL10956658 | 0.80 | CYP3A4 (0.39) | TDP1CYP3A4TSHRLMNAHTT | |
| SCHEMBL11622432 | 0.80 | CYP3A4 (0.45) | TDP1KDM4ECYP3A4TSHRMAPK1 | |
| SCHEMBL11782330 | 0.80 | CYP3A4 (0.45) | TDP1CYP3A4TSHRMAPK1TRPA1 | |
| SCHEMBL2892281 | 0.80 | ALDH1A1 (0.47) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL7531828 | 0.79 | MAPK1 (0.41) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL1133882 | 0.78 | MAPK1 (0.38) | TDP1ALDH1A1KDM4EPTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023033890-A1 | NITROGEN-CONTAINING COMPOUNDS AS ADDITIVES FOR SILICON-BASED LI-ION BATTERIES | ENEVATE CORPORATION (US) | 2023-03-09 | — | — | WO | claimed |
| EP-4747242-A1 | HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE | Horizon Therapeutics Ireland Dac (IE) | 2026-05-27 | — | — | EP | disclosed |
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| US-20250145585-A1 | HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2025-05-08 | — | — | US | disclosed |
| WO-2025019715-A1 | HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2025-01-23 | — | — | WO | disclosed |
| EP-3774961-B1 | ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2025-01-15 | — | — | EP | disclosed |
| WO-2024236000-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2024-11-21 | — | — | WO | disclosed |
| EP-4464727-A1 | ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| US-20240150515-A1 | Low Viscosity Catalyst Compositions for Producing Isocyanurate Polymers | COVESTRO DEUTSCHLAND AG (DE) | 2024-05-09 | — | — | US | disclosed |
| EP-4298140-A1 | LOW VISCOSITY CATALYST COMPOSITIONS FOR PRODUCING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2024-01-03 | — | — | EP | disclosed |
| US-4464386-A | Insecticidal 3-difluoromethoxyphenyl-1-phenylcarbamoyl-2-pyrazolines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0101800-A1 | N-sulfenyl hydantoins | BAYER AG (DE) | 1984-03-07 | — | — | EP | disclosed |
| EP-0078991-A2 | Process for the preparation of mixed trimers of organic isocyanates, mixed trimers obtained by this process and their use in the preparation of polyurethanes | BAYER AG (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0058424-A2 | Pyrazoline derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |
| EP-0007541-B1 | SUBSTITUTED 5-PHENYLCARBAMOYL-BARBITURIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1981-09-09 | — | — | EP | disclosed |
| US-4239762-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0007541-A1 | Substituted 5-phenylcarbamoyl-barbituric acids, process for their preparation and their use as insecticides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |
| US-4174398-A | Combating fungi with 1-alkyl-1-(1,3,4-thiadiazol-2-yl)-3-phenyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |
| US-3984468-A | Herbicidal N-trifluoromethylmercaptophenyl ureas | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145585-A1 | HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE | IGF1R, TSHR, TRHR | TDP1 1086/4885ALDH1A1 1332/4885KDM4E 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.