SCHEMBL1020767

SCHEMBL1020767

COCC(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
HPGD P15428 5/20 0.39
ALDH1A1 P00352 5/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 3/20 0.37
CYP2C19 P33261 1/20 0.37
ALOX12 P18054 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557173 0.94 LMNA (0.43) LMNAHPGDALDH1A1TSHRSMN1; SMN2
SCHEMBL28774875 0.94 LMNA (0.43) LMNAHPGDALDH1A1TSHRSMN1; SMN2
SCHEMBL11874229 0.91 LMNA (0.47) LMNAHPGDALDH1A1TSHRSMN1; SMN2
SCHEMBL4311751 0.85 LMNA (0.47) LMNAHPGDALDH1A1TSHRSMN1; SMN2
SCHEMBL708587 0.84 ALDH1A1 (0.42) LMNAHPGDALDH1A1SMN1; SMN2MAPT
SCHEMBL10878856 0.84 HPGD (0.47) LMNAHPGDALDH1A1TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL1020768 0.83 LMNA (0.46) LMNAHPGDALDH1A1TSHRSMN1; SMN2
SCHEMBL30480271 0.83 LMNA (0.72) LMNAHPGDALDH1A1SMN1; SMN2CYP2C19
SCHEMBL12217873 0.83 LMNA (0.72) LMNAHPGDALDH1A1SMN1; SMN2CYP2C19
SCHEMBL9456178 0.82 TSHR (0.38) LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569600-A New preparation method of iopromide 重庆常捷医药有限公司 2025-03-07 CN claimed
CN-118930450-A Method for preparing iopromide and purifying intermediate 重庆煜洋药业有限公司 2024-11-12 CN claimed
CN-116354843-B Method for synthesizing iopromide 重庆圣华曦药业股份有限公司 2024-11-01 CN claimed
CN-116354843-A Improved method for synthesizing iopromide and application of iopromide in injection 重庆圣华曦药业股份有限公司 2023-06-30 CN claimed
CN-119569600-A New preparation method of iopromide 重庆常捷医药有限公司 2025-03-07 CN disclosed
CN-119569600-A New preparation method of iopromide 重庆常捷医药有限公司 2025-03-07 CN disclosed
CN-118930450-A Method for preparing iopromide and purifying intermediate 重庆煜洋药业有限公司 2024-11-12 CN disclosed
CN-116354843-B Method for synthesizing iopromide 重庆圣华曦药业股份有限公司 2024-11-01 CN disclosed
CN-116354843-B Method for synthesizing iopromide 重庆圣华曦药业股份有限公司 2024-11-01 CN disclosed
CN-116354843-A Improved method for synthesizing iopromide and application of iopromide in injection 重庆圣华曦药业股份有限公司 2023-06-30 CN disclosed
CN-116354843-A Improved method for synthesizing iopromide and application of iopromide in injection 重庆圣华曦药业股份有限公司 2023-06-30 CN disclosed
CN-105636933-B The method for preparing the intermediate of Iopromide 大熊制药株式会社 2017-12-15 CN disclosed
EP-0619744-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1994-10-19 EP disclosed
WO-1994005337-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1994-03-17 WO disclosed
WO-1993010825-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1993-06-10 WO disclosed
US-5191120-A Process for preparing nonionic X-ray contrast agents MALLINCKRODT MEDICAL, INC. (US) 1993-03-02 US disclosed
EP-0504266-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1992-09-23 EP disclosed
US-5075502-A NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1991-12-24 US disclosed
WO-1991009007-A2 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1991-06-27 WO disclosed
US-4364921-A RADIOPACITY SCHERING, AKTIENGESELLSCHAFT (DE) 1982-12-21 US disclosed