SCHEMBL4311751

SCHEMBL4311751

COCC(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)O)c1I

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
MAPK1 P28482 2/20 0.43
TSHR P16473 2/20 0.43
HPGD P15428 4/20 0.41
MAPT P10636 2/20 0.41
CYP2C19 P33261 1/20 0.41
ALOX12 P18054 1/20 0.41
HTT P42858 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
CSNK2A2 P19784 1/20 0.37
CSNK2A1 P68400 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1020768 0.98 LMNA (0.46) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL29557173 0.92 LMNA (0.43) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11406813 0.91 LMNA (0.47) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11879797 0.91 LMNA (0.55) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11522677 0.86 LMNA (0.52) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL10878856 0.85 HPGD (0.47) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11695859 0.85 LMNA (0.48) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11593788 0.85 LMNA (0.48) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL11545376 0.85 LMNA (0.46) LMNAMAPK1TSHRHPGDMAPT
SCHEMBL1020767 0.85 LMNA (0.46) LMNAMAPK1TSHRHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009134030-A1 NOVEL PROCESS FOR PREPARATION OF IOPROMIDE LG LIFE SCIENCES LTD. (KR) 2009-11-05 WO claimed
US-4364921-A RADIOPACITY SCHERING, AKTIENGESELLSCHAFT (DE) 1982-12-21 US claimed
EP-0015867-B1 DIAMIDES OF TRIIODO-ISOPHTHALIC ACIDS, THEIR PREPARATION AND X-RAY CONTRAST AGENTS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1982-05-19 EP claimed
CN-110015972-B Preparation method of iopromide intermediate 台州学院 2022-05-03 CN disclosed
WO-2015060657-A1 A METHOD FOR PREPARING AN INTERMEDIATE OF IOPROMIDE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2015-04-30 WO disclosed
CN-103570580-B Preparation method of high-purity iopromide BEIJING JINGWEI XINKANG PHARMACEUTICAL TECHNOLOGY DEV CO LTD 2015-04-01 CN disclosed
CN-103570580-A Preparation method of high-purity iopromide BEIJING JINGWEI XINKANG MEDICAL TECHNOLOGY DEV CO LTD 2014-02-12 CN disclosed
CN-102015624-B Preparation method of iopromide LG LIFE SCIENCES LTD 2013-11-06 CN disclosed
US-8420858-B2 Process for preparation of iopromide LG LIFE SCIENCES LTD. (KR) 2013-04-16 US disclosed
US-8420858-B2 Process for preparation of iopromide LG LIFE SCIENCES LTD. (KR) 2013-04-16 US disclosed
CN-102015624-A New preparation method of iopromide LG LIFE SCIENCES LTD 2011-04-13 CN disclosed
WO-2009134030-A1 NOVEL PROCESS FOR PREPARATION OF IOPROMIDE LG LIFE SCIENCES LTD. (KR) 2009-11-05 WO disclosed
WO-2009134030-A1 NOVEL PROCESS FOR PREPARATION OF IOPROMIDE LG LIFE SCIENCES LTD. (KR) 2009-11-05 WO disclosed
US-4364921-A RADIOPACITY SCHERING, AKTIENGESELLSCHAFT (DE) 1982-12-21 US disclosed