Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10207887 | 0.95 | KDM1A (0.37) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL10207868 | 0.89 | ACACB (0.44) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL10207914 | 0.87 | ACACB (0.33) | ACACBACACAEDNRBEDNRA | |
| SCHEMBL12134150 | 0.86 | HDAC1 (0.33) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL10207888 | 0.84 | ACACB (0.44) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL12134153 | 0.83 | HDAC1 (0.36) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL10207903 | 0.82 | MAOA (0.38) | KDM1AMAOAMAOBIDH1HDAC1 | |
| SCHEMBL468935 | 0.80 | ACACB (0.36) | ACACBACACAEDNRBEDNRA | |
| SCHEMBL10207879 | 0.80 | HDAC1 (0.34) | KDM1AMAOAMAOBACACBACACA | |
| SCHEMBL10079509 | 0.79 | ACACB (0.33) | ACACBACACAEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735322-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| US-8735322-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| US-20120035053-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| US-20120035053-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| WO-2010046194-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035053-A1 | NOVEL HERBICIDES | DDT, HCAR3, HPD | KDM1A 780/4885MAOA 3398/4885MAOB 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.