Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22627334 | 0.93 | TSHR (0.86) | TSHRTDP1KCNA3USP2ATM | |
| SCHEMBL12394889 | 0.92 | TSHR (0.84) | TSHRTDP1EPHX1 | |
| SCHEMBL10044269 | 0.92 | TSHR (0.84) | TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL15171908 | 0.92 | TSHR (0.84) | TSHRTDP1 | |
| SCHEMBL16684434 | 0.91 | TSHR (0.84) | TSHRTDP1KCNA3 | |
| SCHEMBL13631002 | 0.91 | TSHR (0.84) | TSHRTDP1OPRM1OPRL1 | |
| SCHEMBL10044232 | 0.91 | TSHR (0.84) | TSHRTDP1KCNA3OPRM1OPRL1 | |
| SCHEMBL13867711 | 0.90 | TSHR (0.82) | TSHRTDP1EPHX1 | |
| SCHEMBL22627154 | 0.90 | TSHR (0.82) | TSHRTDP1KCNA3USP2ATM | |
| SCHEMBL17552150 | 0.89 | TSHR (0.80) | TSHRTDP1EPHX1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4431490-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2024-09-18 | — | — | EP | disclosed |
| US-20230167364-A1 | METHOD FOR MANUFACTURING POLYMER DISPERSED LIQUID CRYSTAL DISPLAY ELEMENT, AND POLYMER DISPERSED LIQUID CRYSTAL DISPLAY ELEMENT | DIC CORPORATION (JP) | 2023-06-01 | — | — | US | disclosed |
| US-20230167364-A1 | METHOD FOR MANUFACTURING POLYMER DISPERSED LIQUID CRYSTAL DISPLAY ELEMENT, AND POLYMER DISPERSED LIQUID CRYSTAL DISPLAY ELEMENT | DIC CORPORATION (JP) | 2023-06-01 | — | — | US | disclosed |
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |
| EP-3838892-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2022-10-12 | — | — | EP | disclosed |
| US-11360342-B2 | Light-scattering liquid crystal device | DIC CORPORATION (JP) | 2022-06-14 | — | — | US | disclosed |
| US-11278489-B2 | Cosmetic composition for nails, method of using same, and cosmetic resin for nails | MENICON CO., LTD. (JP) | 2022-03-22 | — | — | US | disclosed |
| EP-3293173-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-20210223586-A1 | LIGHT-SCATTERING LIQUID CRYSTAL DEVICE | DIC CORPORATION (JP) | 2021-07-22 | — | — | US | disclosed |
| EP-3838892-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Kabushiki Kaisha (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-0323514-B1 | PROCESS FOR PREPARING ISOCYANATE COMPOUNDS | DAICEL CHEM (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5326903-A | Thermal decomposition of carbamate | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5284969-A | Thermal decomposition of the corresponding carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0555628-A2 | Process for preparing isocyanates | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0542106-A2 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0244620-B1 | PROCESS FOR THE PREPARATION OF ISOPHORONE DIISOCYANATE FROM ISOPHORONE DICARBAMYL ESTERS USING HIGHLY SELECTIVE SNO2 OR CUO CATALYSTS | AMERICAN CYANAMID COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0323514-A1 | PROCESS FOR PREPARING ISOCYANATE COMPOUNDS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |
| EP-0244620-A1 | Process for the preparation of isophorone diisocyanate from isophorone dicarbamyl esters using highly selective SnO2 or CuO catalysts | AMERICAN CYANAMID COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278489-B2 | Cosmetic composition for nails, method of using same, and cosmetic resin for nails | POLR1C, NACA, PIK3C3 | TSHR 2976/4885TDP1 2300/4885KCNA3 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.