SCHEMBL15171908

SCHEMBL15171908

COC(=O)NC1CC(C)(C)CC(C)(CNC(=O)OCF)C1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.84
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394889 0.95 TSHR (0.84) TSHRTDP1
SCHEMBL1021081 0.92 TSHR (1.00) TSHRTDP1
SCHEMBL13171313 0.90 TSHR (0.68) TSHRTDP1
SCHEMBL13171329 0.90 TSHR (0.80) TSHRTDP1
SCHEMBL1753416 0.89 TSHR (0.71) TSHRTDP1
SCHEMBL19343438 0.89 TSHR (0.67) TSHRTDP1
SCHEMBL10044269 0.89 TSHR (0.84) TSHRTDP1
SCHEMBL10044232 0.89 TSHR (0.84) TSHRTDP1
SCHEMBL16641682 0.88 TSHR (0.66) TSHRTDP1
SCHEMBL92121 0.88 TSHR (0.66) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8945441-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-02-03 US disclosed
US-20140131915-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-05-15 US disclosed
US-8662878-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-03-04 US disclosed
US-20130202729-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-08-08 US disclosed