SCHEMBL10214

SCHEMBL10214

COOC(=O)CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 6/20 0.50
PHF8 Q9UPP1 5/20 0.50
KDM2A Q9Y2K7 5/20 0.50
KDM5C P41229 4/20 0.50
KDM6B O15054 3/20 0.50
LMNA P02545 5/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
TSHR P16473 4/20 0.46
SLC15A2 Q16348 1/20 0.43
ALDH1A1 P00352 1/20 0.39
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MAPK1 P28482 1/20 0.38
SLC13A3 Q8WWT9 1/20 0.38
OR51E2 Q9H255 1/20 0.38
KDM4E B2RXH2 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11672385 0.97 EGLN1 (0.48) EGLN1PHF8KDM2AKDM5CKDM6B
Butane SCHEMBL2855830 0.93 FFAR3 (0.46) EGLN1PHF8KDM2AKDM5CKDM6B
SCHEMBL10211 0.89 TSHR (0.56) EGLN1PHF8KDM2AKDM5CKDM6B
SCHEMBL3446330 0.85 TSHR (0.60) LMNATSHRALDH1A1OR51E2SLC22A6
SCHEMBL3447339 0.85 TSHR (0.67) LMNATSHRALDH1A1OR51E2SLC22A6
Triethylene Glycol SCHEMBL18274766 0.84 MEN1 (0.41) EGLN1PHF8KDM2AKDM5CKDM6B
SCHEMBL28787075 0.83 TSHR (0.58) LMNATSHRALDH1A1OR51E2SLC22A6
SCHEMBL3446838 0.83 TSHR (0.58) LMNATSHRALDH1A1OR51E2SLC22A6
Hydrochloric Acid SCHEMBL31163979 0.83 TSHR (0.64) LMNATSHRALDH1A1OR51E2SLC22A6
SCHEMBL3446322 0.83 TSHR (0.58) LMNATSHRALDH1A1OR51E2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2731431-B1 ENHANCED ANTIMICROBIAL PERACID COMPOSITIONS AND METHODS OF USE AT REDUCED TEMPERATURES IN ASEPTIC CLEANING ECOLAB USA INC (US) 2019-08-21 EP disclosed
EP-3492982-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, METHOD FOR PRODUCING CURED FILM, METHOD FOR PRODUCING LAMINATE, AND SEMICONDUCTOR DEVICE FUJIFILM Corporation (JP) 2019-06-05 EP disclosed
US-10240447-B2 Method for optimizing conductivity in a hydraulic fracturing operation BAKER HUGHES, A GE COMPANY, LLC (US) 2019-03-26 US disclosed
US-10138418-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES, A GE COMPANY, LLC (US) 2018-11-27 US disclosed
US-20180044579-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES, A GE COMPANY, LLC (US) 2018-02-15 US disclosed
US-9828844-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHTES, a GE company, LLC (US) 2017-11-28 US disclosed
US-9809742-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES, A GE COMPANY, LLC (US) 2017-11-07 US disclosed
US-9802846-B2 Treating and recylcing oilfield waste water BAKER HUGHES, A GE COMPANY, LLC (US) 2017-10-31 US disclosed
US-9796914-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES INCORPORATED (US) 2017-10-24 US disclosed
US-9670080-B2 Composition and method for treating oilfield water BAKER HUGHES INCORPORATED (US) 2017-06-06 US disclosed
WO-2003005817-A2 HIGH CONCENTRATION MONOESTER PEROXY DICARBOXYLIC ACID COMPOSITIONS, USE SOLUTIONS, AND METHODS EMPLOYING THEM ECOLAB INC. (US) 2003-01-23 WO disclosed
WO-2003005818-A1 IN SITUMONO-OR DIESTER DICARBOXYLATE COMPOSITIONS ECOLAB INC. (US) 2003-01-23 WO disclosed
US-20020192340-A1 Method and system for reducing microbial burden on a food product ECOLAB USA INC. 2002-12-19 US disclosed
US-20020168422-A1 Two solvent antimicrobial compositions and methods employing them ECOLAB USA INC. 2002-11-14 US disclosed
WO-2002088076-A2 STABILIZED ESTER PEROXYCARBOXYLIC ACID COMPOSITIONS ECOLAB INC. (US) 2002-11-07 WO disclosed
US-20020128312-A1 Adding a C2 or higher alcohol as a stabilizer ECOLAB USA INC. 2002-09-12 US disclosed
WO-2002060280-A2 METHOD AND SYSTEM FOR REDUCING MICROBIAL BURDEN ON A FOOD PRODUCT BY APPLICATION OF ANTIMICROBIAL AGENT AND IRRADIATION TO THE FOOD PRODUCT ECOLAB INC. (US) 2002-08-08 WO disclosed
US-5565447-A ALMOTRIPTAN MALATE; TREATING HEADACHES, MOVEMENT DISORDERS, DEPRESSION, ANXIETY LABORATORIOS ALMIRALL S.A. (ES) 1996-10-15 US disclosed
EP-0206375-A1 Liquid cleaning and softening compositions UNILEVER N.V. (NL) 1986-12-30 EP disclosed
EP-0203660-A1 Liquid cleaning and softening compositions UNILEVER N.V. (NL) 1986-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128312-A1 Adding a C2 or higher alcohol as a stabilizer ADH1C, ADH1A, PCCA EGLN1 3045/4885PHF8 2021/4885KDM2A 1351/4885
US-20020168422-A1 Two solvent antimicrobial compositions and methods employing them TAS2R50, HDHD5, CEL EGLN1 931/4885PHF8 2649/4885KDM2A 2932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.