SCHEMBL7054607

SCHEMBL7054607

COOC(=O)CCC(=O)OC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.39
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10211 0.84 TSHR (0.56) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL3622179 0.82 ALDH1A1 (0.45) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL9490448 0.81 TSHR (0.36) TSHRHSD17B10
SCHEMBL8741901 0.80 TSHR (0.68) TSHRALDH1A1LMNAKDM4EMAPT
SCHEMBL10214 0.80 EGLN1 (0.50) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL11685071 0.79 TSHR (0.35) TSHRHSD17B10
SCHEMBL11672385 0.78 EGLN1 (0.48) TSHRALDH1A1KDM6BKDM5CEGLN1
SCHEMBL11032566 0.78 TSHR (0.65) TSHRALDH1A1LMNAKDM4EMAPT
SCHEMBL5700569 0.78 TSHR (0.65) TSHRALDH1A1LMNAKDM4EMAPT
Water SCHEMBL11684196 0.77 TSHR (0.33) TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3833731-A1 COMPOSITIONS COMPRISING A LIPOLYTIC ENZYME VARIANT AND METHODS OF USE THEREOF Danisco US Inc. (US) 2021-06-16 EP disclosed
WO-2020046613-A1 COMPOSITIONS COMPRISING A LIPOLYTIC ENZYME VARIANT AND METHODS OF USE THEREOF DANISCO US INC (US) 2020-03-05 WO disclosed
EP-1432759-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-06-30 EP disclosed
WO-2003020819-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2003-03-13 WO disclosed
US-5488146-A SULFONATING MALEIC ANHYDRIDE WITH SULFUR TRIOXIDE; ADDING GLYCOLIC ACID; SALT FORMATION WITH ALKALINE EARTH OR ALKALI METAL HYDROXIDE; PRECIPITATING; ION EXCHANGING WITH SODIUM SALT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-01-30 US disclosed
EP-0237111-B1 DETERGENT BLEACH COMPOSITION, BLEACHING COMPOSITIONS AND BLEACH ACTIVATORS UNILEVER N.V. (NL) 1993-01-20 EP disclosed
US-4988363-A WASHING FABRICS USING ORGANIC PEROXYACIDS AS BLEACHES; CONTROLLING PH LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-01-29 US disclosed
EP-0290081-B1 IMPROVED DETERGENT BLEACH COMPOSITION AND METHOD OF CLEANING FABRICS UNILEVER N.V. (NL) 1990-10-31 EP disclosed
EP-0178006-B1 LIQUID DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1990-09-12 EP disclosed
EP-0290081-A1 Improved detergent bleach composition and method of cleaning fabrics UNILEVER N.V. (NL) 1988-11-09 EP disclosed
EP-0237111-A2 Detergent bleach composition, bleaching compositions and bleach activators UNILEVER N.V. (NL) 1987-09-16 EP disclosed
EP-0178006-A2 Liquid detergent compositions UNILEVER N.V. (NL) 1986-04-16 EP disclosed
US-3914297-A Carboxy methyloxy succinates LEVER BROTHERS LTD 1975-10-21 US disclosed