Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653231 | 0.74 | CHRM3 (0.31) | — | |
| SCHEMBL23653229 | 0.74 | — | — | |
| SCHEMBL20403515 | 0.71 | — | — | |
| SCHEMBL562034 | 0.67 | — | — | |
| SCHEMBL14604953 | 0.66 | CYP2A6 (0.31) | — | |
| SCHEMBL14567142 | 0.65 | ALDH1A1 (0.30) | DYRK1A | |
| SCHEMBL3464607 | 0.65 | — | — | |
| SCHEMBL24254074 | 0.62 | CHRM3 (0.30) | — | |
| SCHEMBL8029661 | 0.62 | HTR6 (0.31) | — | |
| SCHEMBL8272745 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087861-A1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2012-06-28 | — | — | WO | disclosed |