Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12134121 | 0.77 | DYRK1A (0.43) | DYRK1A | |
| SCHEMBL8029661 | 0.76 | HTR6 (0.31) | HTR6 | |
| SCHEMBL14279000 | 0.75 | DYRK1A (0.39) | DYRK1A | |
| SCHEMBL13964555 | 0.72 | DYRK1A (0.40) | DYRK1A | |
| SCHEMBL4240710 | 0.69 | HTR6 (0.38) | HTR6 | |
| SCHEMBL13107417 | 0.68 | DYRK1A (0.33) | DYRK1A | |
| SCHEMBL12998335 | 0.67 | HTR1A (0.33) | — | |
| SCHEMBL12019594 | 0.66 | CHRM3 (0.31) | — | |
| SCHEMBL10212282 | 0.65 | DYRK1A (0.32) | DYRK1A | |
| SCHEMBL12019574 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081931-B1 | [1,2,4]Triazolo[4,3-a]pyridine derivatives useful as inhibitors of the hepatocyte growth factor receptor | AMGEN INC (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2007026097-A1 | NOVEL INDOLE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2007-03-08 | — | — | WO | disclosed |