Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 14/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10212801 | 0.87 | HRH3 (0.45) | SORDWNT1GSK3BDYRK1A | |
| SCHEMBL509308 | 0.84 | SORD (0.52) | SORDWNT1GSK3BDYRK1AHRH4 | |
| SCHEMBL10211810 | 0.84 | HRH4 (0.50) | SORDHRH4 | |
| SCHEMBL510428 | 0.83 | HRH4 (0.40) | SORDWNT1GSK3BDYRK1AHRH4 | |
| SCHEMBL10214505 | 0.81 | CXCR4 (0.44) | SORD | |
| SCHEMBL10214439 | 0.79 | PIK3CA (0.46) | SORDOGA | |
| SCHEMBL509749 | 0.70 | SORD (0.56) | SORDHRH4 | |
| SCHEMBL509880 | 0.69 | HRH3 (0.41) | SORDWNT1GSK3BDYRK1AHRH4 | |
| SCHEMBL23916630 | 0.66 | WNT1 (0.40) | WNT1GSK3BDYRK1AHRH4 | |
| SCHEMBL4197090 | 0.66 | HRH3 (0.46) | SORDHRH4OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028979-A1 | 2-(PIPERIDIN-1-YL)-4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028979-A1 | 2-(PIPERIDIN-1-YL)-4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | TLR5, TLR2, PIR | SORD 284/4885WNT1 4422/4885GSK3B 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.