Sugi Predict

Sugi Predict / Compounds / SCHEMBL10214014

SCHEMBL10214014

SCHEMBL10214014

COB(C)OCc1cc(F)ccc1Br

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 1/20 0.33
▸ HTR2A P28223 2/20 0.33
▸ IDO1 P14902 2/20 0.32
▸ AGXT P21549 2/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ FFAR1 O14842 1/20 0.31
▸ FFAR4 Q5NUL3 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ SLC6A4 P31645 2/20 0.30
▸ HTR1A P08908 1/20 0.30
▸ AMY1A P0DUB6 2/20 0.30
▸ PKM P14618 1/20 0.30
▸ ACHE P22303 1/20 0.30
▸ KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10269137 0.85 IDO1 (0.36) NR3C1HTR2AIDO1AGXTMAPK1
SCHEMBL13224667 0.83 DPP4 (0.30) —
SCHEMBL10214013 0.82 PKM (0.34) NR3C1HTR2AIDO1AGXTFFAR1
SCHEMBL10214033 0.81 IDO1 (0.32) HTR2AIDO1AGXTMEN1KMT2A
SCHEMBL1723567 0.79 NR3C1 (0.37) NR3C1HTR2AIDO1AGXTMAPK1
SCHEMBL30910900 0.79 NR3C1 (0.37) NR3C1HTR2AIDO1AGXTMAPK1
SCHEMBL14470682 0.78 PKM (0.36) NR3C1IDO1AGXTMEN1KMT2A
SCHEMBL10214090 0.77 — —
SCHEMBL596487 0.75 IDO1 (0.33) NR3C1IDO1AGXT
SCHEMBL500146 0.73 NR3C1 (0.34) NR3C1HTR2AIDO1AGXTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-03-09 — — US disclosed
US-9572823-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-21 — — US disclosed
US-9566290-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9566289-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9549938-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-01-24 — — US disclosed
US-20160228463-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-08-11 — — US disclosed
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-07-21 — — US disclosed
US-20160184334-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-06-30 — — US disclosed
US-20160151399-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-06-02 — — US disclosed
US-9353133-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2016-05-31 — — US disclosed
US-8722917-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2014-05-13 — — US disclosed
US-20130210770-A1 PHARMACEUTICAL FORMULATIONS ANACOR PHARMACEUTICALS, INC. (US) 2013-08-15 — — US disclosed
US-20130064783-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-14 — — US disclosed
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20120289686-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2012-11-15 — — US disclosed
US-8115026-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2012-02-14 — — US disclosed
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-21 — — US disclosed
US-7767657-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2010-08-03 — — US disclosed
US-20070155699-A1 Boron-containing small molecules ANACOR PHARMACEUTICALS (US) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20160151399-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20130210770-A1 PHARMACEUTICAL FORMULATIONS DPM1, POLR1C, ETF1 NR3C1 3390/4885HTR2A 1885/4885IDO1 46/4885
US-20160228463-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20120289686-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20070155699-A1 Boron-containing small molecules ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20130064783-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885
US-20160184334-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 NR3C1 3158/4885HTR2A 3715/4885IDO1 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.