Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311394 | 0.89 | P2RX7 (0.58) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL1005866 | 0.89 | P2RX7 (0.58) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL1190522 | 0.89 | P2RX7 (0.58) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL6179972 | 0.87 | P2RX7 (0.57) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL6179978 | 0.87 | P2RX7 (0.57) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL3337871 | 0.86 | P2RX7 (0.57) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL10270030 | 0.86 | P2RX7 (0.57) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL3333492 | 0.86 | P2RX7 (0.56) | P2RX7HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL1189916 | 0.85 | P2RX7 (0.53) | P2RX7BRD4HCRTR1HCRTR2MEN1 | |
| SCHEMBL2907566 | 0.85 | P2RX7 (0.53) | P2RX7BRD4HCRTR1HCRTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053148-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053148-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, FABP1, EIF2AK2 | P2RX7 3918/4885BRD4 1881/4885HCRTR1 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.