Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023688 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1PGRKDM4EMEN1 | |
| SCHEMBL1022880 | 0.81 | BRD4 (0.39) | PTGS2PTGS1KDM4EMAPTPKM | |
| SCHEMBL1022350 | 0.80 | PTGS2 (0.49) | PTGS2PTGS1PGR | |
| SCHEMBL1023762 | 0.80 | HSD17B1 (0.39) | PTGS2KDM4EPKM | |
| SCHEMBL1021263 | 0.80 | MAPK1 (0.35) | SIGMAR1AHRSLC6A3AKR1C2AKR1C1 | |
| SCHEMBL1021262 | 0.80 | MAPK1 (0.35) | SIGMAR1AHRSLC6A3AKR1C2AKR1C1 | |
| SCHEMBL1022344 | 0.79 | RARB (0.45) | MEN1MAPTKMT2A | |
| SCHEMBL1022415 | 0.78 | CYP19A1 (0.45) | KDM4EMAPTPDE3BPDE3A | |
| SCHEMBL1022110 | 0.78 | PTGS1 (0.46) | PTGS2PTGS1USP2HTT | |
| SCHEMBL1021653 | 0.77 | KDM4E (0.37) | PGRKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |