Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19841763 | 0.82 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL19841645 | 0.82 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL8469278 | 0.81 | TDP1 (0.50) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL2734307 | 0.79 | CA1 (0.43) | TDP1KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL17041409 | 0.79 | CHRNB2 (0.48) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL19841685 | 0.79 | CHRNB2 (0.51) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL17041810 | 0.79 | CHRNB2 (0.48) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL532785 | 0.78 | CARM1 (0.61) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL13286850 | 0.78 | PPM1B (0.56) | TDP1KMT2AMAPK1HIF1ACHRNB2 | |
| SCHEMBL8447322 | 0.78 | CARM1 (0.61) | TDP1KMT2AMAPK1HIF1ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398317-B1 | ALICYCLIC COMPOUND FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2011-01-12 | — | — | EP | disclosed |
| EP-1319966-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-7301705-B2 | Alicyclic compound for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7183441-B2 | Method for producing vicinal dithiol | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7009031-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2006-03-07 | — | — | US | disclosed |
| US-20050187413-A1 | Method for producing vicinal dithiol | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-1564207-A1 | Method for producing vicinal dithiol | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-20040158031-A1 | Alicyclic compound for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1398317-A1 | ALICYCLIC COMPOUND FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-20040024165-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1319966-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187413-A1 | Method for producing vicinal dithiol | TST, STS, CTH | TDP1 3996/4885KMT2A 3265/4885MAPK1 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.