Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31644579 | 0.86 | ACHE (0.74) | ACHETDP1EPHX2EPHX1 | |
| SCHEMBL1019101 | 0.86 | ACHE (0.74) | ACHETDP1EPHX2EPHX1 | |
| Methacrylic Acid SCHEMBL6009467 | 0.84 | ACHE (0.46) | ACHETDP1EPHX2 | |
| Methacrylic Acid SCHEMBL4084174 | 0.84 | ACHE (0.56) | ACHEEPHX2 | |
| SCHEMBL10898613 | 0.81 | ACHE (0.86) | ACHEEPHX2EPHX1 | |
| SCHEMBL18674258 | 0.81 | ACHE (0.86) | ACHEEPHX2EPHX1 | |
| SCHEMBL10579744 | 0.81 | ACHE (0.86) | ACHEEPHX2EPHX1 | |
| SCHEMBL3440757 | 0.81 | ACHE (0.86) | ACHEEPHX2EPHX1 | |
| Methacrylic Acid SCHEMBL8928145 | 0.80 | ACHE (0.49) | ACHETDP1 | |
| Methacrylic Acid SCHEMBL31735092 | 0.80 | ACHE (0.49) | ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472218-B1 | THREE DIMENSIONAL FABRICATING MATERIAL SYSTEMS AND METHODS FOR PRODUCING LAYERED DENTAL PRODUCTS | DENTSPLY SIRONA INC (US) | 2023-08-09 | — | — | EP | claimed |
| EP-3027165-B1 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2021-11-17 | — | — | EP | claimed |
| CN-105722494-B | Impact-modified denture base composition | 登士柏国际公司 | 2020-11-03 | — | — | CN | claimed |
| EP-2467092-B1 | HYBRID POLYMER NETWORK COMPOSITIONS FOR USE IN DENTAL APPLICATIONS | DENTSPLY SIRONA INC (US) | 2019-08-28 | — | — | EP | claimed |
| US-10299896-B2 | Three-dimensional fabricating material systems and methods for producing layered dental products | DENTSPLY SIRONA INC. (US) | 2019-05-28 | — | — | US | claimed |
| US-20170360534-A1 | THREE-DIMENSIONAL FABRICATING MATERIAL SYSTEMS AND METHODS FOR PRODUCING LAYERED DENTAL PRODUCTS | DENTSPLY SIRONA INC. (US) | 2017-12-21 | — | — | US | claimed |
| EP-3027165-A1 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS | Dentsply International Inc. (US) | 2016-06-08 | — | — | EP | claimed |
| US-20150038634-A1 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS | DENTSPLY INTERNATIONAL INC. | 2015-02-05 | — | — | US | claimed |
| WO-2015017556-A1 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2015-02-05 | — | — | WO | claimed |
| US-8765836-B2 | Hybrid polymer network compositions for use in dental applications | DENTSPLY INTERNATIONAL INC. (US) | 2014-07-01 | — | — | US | claimed |
| EP-2467092-A2 | HYBRID POLYMER NETWORK COMPOSITIONS FOR USE IN DENTAL APPLICATIONS | DENTSPLY International Inc. (US) | 2012-06-27 | — | — | EP | claimed |
| US-20120157566-A1 | Hybrid polymer network compositions for use in dental applications | SUN BENJAMIN J (US) | 2012-06-21 | — | — | US | claimed |
| EP-1924235-B1 | METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INT INC (US) | 2011-01-12 | — | — | EP | claimed |
| WO-2010087954-A2 | HYBRID POLYMER NETWORK COMPOSITIONS FOR USE IN DENTAL APPLICATIONS | DENTSPLY INTERNATIONAL INC. (US) | 2010-08-05 | — | — | WO | claimed |
| US-20080230167-A1 | Adhesive and method for binding artificial plastic teeth | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2008-09-25 | — | — | US | claimed |
| EP-1924235-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL, INC. (US) | 2008-05-28 | — | — | EP | claimed |
| US-20080041520-A1 | Adhesive and method for binding artificial plastic teeth | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2008-02-21 | — | — | US | claimed |
| WO-2007022503-A2 | ADHESIVE AND METHOD FOR BONDING ARTIFICIAL PLASTIC TEETH | DENTSPLY INTERNATIONAL INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-12042549-B2 | Photopolymerizable resin compositions for durable dental prosthetic and restorative articles | DENTSPLY SIRONA INC. (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2005027773-A1 | METHOD OF MAKING A DENTAL PRODUCT FRAME | DENTSPLY INTERNATIONAL INC. (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12042549-B2 | Photopolymerizable resin compositions for durable dental prosthetic and restorative articles | KDM3A, PSMA3, NOX3 | ACHE 2496/4885TDP1 1614/4885EPHX2 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.