Methacrylic Acid

Methacrylic Acid

SCHEMBL8928145

C=C(C)C(=O)O.CCOC(=O)NCCCO

nearest known ligand 0.49

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.49
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
GLA P06280 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL31735092 1.00 ACHE (0.49) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL4811629 0.88 ACHE (0.60) ACHEHDAC3HDAC4HDAC1HDAC7
Methacrylic Acid SCHEMBL2052203 0.87 ACHE (0.53) ACHE
Methacrylic Acid SCHEMBL28074000 0.84 ACHE (0.44) ACHEHDAC3HDAC4HDAC1HDAC7
Acrylic Acid SCHEMBL28960989 0.83 ACHE (0.49) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL4816959 0.82 ACHE (0.62) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL8425986 0.80 ACHE (0.66) ACHETDP1
Methacrylic Acid SCHEMBL29020791 0.80 GAA (0.43) ACHEHDAC3HDAC4HDAC1HDAC7
Methacrylic Acid SCHEMBL28459771 0.80 GAA (0.43) ACHEHDAC3HDAC4HDAC1HDAC7
Methacrylic Acid SCHEMBL1021648 0.80 ACHE (0.62) ACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495269-B1 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK & CHEMICALS (JP) 1997-03-05 EP disclosed
US-5292833-A Polyepoxide compound, carbamate compound and catalyst DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-08 US disclosed
WO-1992012192-A2 THERMOSETTING REACTIVE RESIN MIXTURE, MOULDED ARTICLE AND COATING MADE THEREFROM DAINIPPON INK & CHEMICALS, INC. (JP) 1992-07-23 WO disclosed
EP-0495269-A2 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-22 EP disclosed