Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176699 | 0.85 | ALDH1A1 (0.46) | KCNQ3KCNQ2PRCPLMNAALDH1A1 | |
| SCHEMBL13871668 | 0.82 | ALDH1A1 (0.45) | KCNQ3KCNQ2PRCPLMNAALDH1A1 | |
| SCHEMBL10216634 | 0.78 | PRCP (0.36) | KCNQ3KCNQ2PRCPLMNAALDH1A1 | |
| SCHEMBL300736 | 0.77 | CNR2 (0.43) | — | |
| SCHEMBL3467155 | 0.75 | MEN1 (0.42) | LMNAALDH1A1PTGER4HPGDSMN1; SMN2 | |
| SCHEMBL14027872 | 0.75 | CYP2D6 (0.32) | PRCPLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL300548 | 0.75 | EPHX2 (0.43) | ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL300503 | 0.75 | EPHX2 (0.43) | ALDH1A1SMN1; SMN2SMYD3 | |
| SCHEMBL4709881 | 0.75 | POLB (0.39) | LMNAPKMPTGER4CTSK | |
| SCHEMBL4709575 | 0.74 | PTGER4 (0.38) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |