Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022415 | 0.88 | CYP19A1 (0.45) | KDM4EMAPK1 | |
| SCHEMBL1022350 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL1022426 | 0.82 | HSD17B1 (0.47) | MGLLPTGS2PTGS1CYP17A1KDM4E | |
| SCHEMBL1021341 | 0.82 | MGLL (0.47) | MGLLPTGS2PTGS1CYP17A1ERN1 | |
| SCHEMBL1021340 | 0.82 | MGLL (0.47) | MGLLPTGS2PTGS1CYP17A1ERN1 | |
| SCHEMBL1021324 | 0.82 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL1021368 | 0.79 | RARB (0.41) | PTGS2PTGS1LMNAHPGD | |
| SCHEMBL1022110 | 0.78 | PTGS1 (0.46) | PTGS2PTGS1HPGD | |
| SCHEMBL1022157 | 0.77 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL1022920 | 0.77 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |