SCHEMBL10219286

SCHEMBL10219286

C=CC(=O)OC(C)CCC1CC(C)OC1=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.41
KDM4E B2RXH2 2/20 0.38
HTT P42858 4/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
BLM P54132 1/20 0.36
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
NAAA Q02083 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12509461 0.78 POLB (0.32) TSHR
SCHEMBL12501610 0.73 TSHR (0.31) TSHR
SCHEMBL12332916 0.72 TSHR (0.37) TSHR
SCHEMBL3667633 0.72 TSHR (0.37) ALDH1A1TSHR
SCHEMBL672062 0.70 TSHR (0.50) ALDH1A1TP53SMN1; SMN2TSHR
SCHEMBL14413242 0.69 TSHR (0.37) TSHR
SCHEMBL7080620 0.69 HSD11B1 (0.35) TSHR
SCHEMBL28555548 0.68 TSHR (0.36) TSHR
SCHEMBL685651 0.67 KMT2A (0.33) ATMHTTKMT2AGAAALDH1A1
SCHEMBL664779 0.67 ATM (0.40) ATMKDM4EHTTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120052443-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20110091808-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091808-A1 PHOTORESIST COMPOSITION ASIC1, ASIC3, SUN2 ATM 2120/4885KDM4E 3478/4885HTT 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.