Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020565 | 0.84 | PTGS1 (0.44) | ALDH1A1PTGS2HTT | |
| SCHEMBL1023950 | 0.81 | PTPN1 (0.42) | PTGS2HTT | |
| SCHEMBL1021059 | 0.80 | TLR8 (0.40) | TLR8ALDH1A1CTSSCTSKMAOB | |
| SCHEMBL1019954 | 0.80 | TLR8 (0.35) | TLR8KIF11PLK1CTSSCTSK | |
| SCHEMBL1019953 | 0.80 | TLR8 (0.35) | TLR8KIF11PLK1CTSSCTSK | |
| SCHEMBL1022110 | 0.80 | PTGS1 (0.46) | ALDH1A1PTGS2HTT | |
| SCHEMBL1020934 | 0.78 | LIPE (0.41) | KIF11PTGS2 | |
| SCHEMBL1022344 | 0.78 | RARB (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1021324 | 0.78 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL1021894 | 0.75 | PTGS1 (0.43) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |