Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 5/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020565 | 0.84 | PTGS1 (0.44) | PTGS1PTGS2HTT | |
| SCHEMBL1023426 | 0.83 | PTGS1 (0.48) | PTGS1PTGS2 | |
| SCHEMBL1021652 | 0.83 | PTGS1 (0.48) | PTGS1PTGS2NR5A2NR5A1 | |
| SCHEMBL1022353 | 0.81 | TLR8 (0.37) | PTGS2HTT | |
| SCHEMBL1022344 | 0.81 | RARB (0.45) | GPR84HSD11B1 | |
| SCHEMBL1022110 | 0.79 | PTGS1 (0.46) | PTGS1PTGS2HTT | |
| SCHEMBL1023988 | 0.79 | DRD2 (0.35) | SCD | |
| SCHEMBL1021653 | 0.79 | KDM4E (0.37) | HTT | |
| SCHEMBL1021752 | 0.79 | RARB (0.55) | PTGS1 | |
| SCHEMBL1022577 | 0.79 | ALDH1A1 (0.43) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |