SCHEMBL102248

SCHEMBL102248

[CH2]CC(CCC)CCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
DNM1 Q05193 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 3/20 0.37
FDPS P14324 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103933 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL199423 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL200435 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL198808 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL199832 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL100485 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL102506 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL101339 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL102172 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL201458 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106893581-B Organic electroluminescent compounds, organic electroluminescence device and its application 南京高光半导体材料有限公司 2019-11-05 CN disclosed
CN-106892915-B Organic compound, organic electroluminescence device and its application 南京高光半导体材料有限公司 2019-02-22 CN disclosed
CN-106892914-B Organic electroluminescent compounds, organic electroluminescence device and its application 南京高光半导体材料有限公司 2019-02-01 CN disclosed
CN-104513510-B Colored curable resin composition 东友精细化工有限公司 2018-07-06 CN disclosed
CN-108101922-A Organic electroluminescent compounds, organic electroluminescence device and its application 南京高光半导体材料有限公司 2018-06-01 CN disclosed
US-8940943-B2 Cosmetic preparations COGNIS IP MANAGEMENT GMBH (DE) 2015-01-27 US disclosed
EP-2601166-A1 COSMETIC PREPARATIONS Cognis IP Management GmbH (DE) 2013-06-12 EP disclosed
US-20130131188-A1 Cosmetic Preparations COGNIS IP MANAGEMENT GMBH (DE) 2013-05-23 US disclosed
EP-2426101-A1 Cosmetic preparations Cognis IP Management GmbH (DE) 2012-03-07 EP disclosed
WO-2012016642-A1 COSMETIC PREPARATIONS COGNIS IP MANAGEMENT GMBH (DE) 2012-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131188-A1 Cosmetic Preparations CYP1B1, CBR1, ACOX3 LMNA 1943/4885DNM1 3903/4885TSHR 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.