SCHEMBL201458

SCHEMBL201458

[CH2]CC(CCC)CCCCCC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
DNM1 Q05193 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 3/20 0.37
FDPS P14324 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103933 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL102248 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL199423 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL200435 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL198808 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL199832 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL100485 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL102506 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL101339 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1
SCHEMBL102172 1.00 LMNA (0.52) LMNADNM1TSHRTHRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
CN-116113657-A Alkoxylated polymeric N- (hydroxyalkyl) amines as wetting agents and as components of defoamer compositions 巴斯夫欧洲公司 2023-05-12 CN disclosed
CN-113200958-B Phthalate ester organic photoelectric compound and preparation method and application thereof 国家纳米科学中心 2022-08-05 CN disclosed
CN-113200958-A Phthalate ester organic photoelectric compound and preparation method and application thereof 国家纳米科学中心 2021-08-03 CN disclosed
US-20210102237-A1 MEANS AND METHODS FOR NUCLEIC ACID TARGET DETECTION BIOTANGENTS LIMITED (GB) 2021-04-08 US disclosed
EP-3759245-A1 MEANS AND METHODS FOR NUCLEIC ACID TARGET DETECTION Biotangents Limited (GB) 2021-01-06 EP disclosed
US-20140329014-A1 Composition and Method for Treating Wood DANIP PTY LTD (AU) 2014-11-06 US disclosed
US-8481736-B2 Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof BASF SE (DE) 2013-07-09 US disclosed
EP-2520570-A1 AMINOPYRIDINE COMPOUND Ube Industries, Ltd. (JP) 2012-11-07 EP disclosed
US-7005261-B1 Method for detecting nucleic acid target sequences involving in vitro transcription from an RNA polymerase promoter BRITISH BIOCELL INTERNATIONAL LIMITED (GB) 2006-02-28 US disclosed
US-6391593-B1 DETECTING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN SAMPLES, INCUBATE WITH PROBES, AMPLIFY NUCLEOTIDE SEQUENCES, DETECT AMPLIFIED NUCLEOTIDE SEQUENCES CYTOCELL LIMITED (GB) 2002-05-21 US disclosed
EP-1200627-A1 METHOD FOR DETECTING NUCLEIC ACID TARGET SEQUENCES INVOLVING IN VITRO TRANSCRIPTION FROM AN RNA POLYMERASE PROMOTER Cytocell Limited (GB) 2002-05-02 EP disclosed
CN-1284070-A Alicyclic acylated heterocyclic derivatives SANKYO CO (JP) 2001-02-14 CN disclosed
WO-2001009377-A1 METHOD FOR DETECTING NUCLEIC ACID TARGET SEQUENCES INVOLVING IN VITRO TRANSCRIPTION FROM AN RNA POLYMERASE PROMOTER CYTOCELL LIMITED (GB) 2001-02-08 WO disclosed
EP-1051515-A2 MODIFIED NUCLEIC ACID PROBES AND USES THEREOF Cytocell Limited (GB) 2000-11-15 EP disclosed
WO-1999037806-A2 MODIFIED NUCLEIC ACID PROBES AND USES THEREOF CYTOCELL LIMITED (GB) 1999-07-29 WO disclosed
EP-0492930-A2 Transdermal delivery of dobutamine ELI LILLY AND COMPANY (US) 1992-07-01 EP disclosed
US-4980371-A TREATMENT OF HIV INFECTIONS/LEUKEMIA; ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS MERRELL DOW PHARMACEUTICALS (US) 1990-12-25 US disclosed
EP-0374886-A2 Antiretroviral furan ketones MERRELL DOW PHARMACEUTICALS INC. (US) 1990-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329014-A1 Composition and Method for Treating Wood SGMS2, SGMS1, C1S LMNA 236/4885DNM1 3359/4885TSHR 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.