Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873970 | 1.00 | MAPK1 (0.35) | MAPK1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL18874376 | 0.90 | MAPK1 (0.33) | MAPK1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL10196009 | 0.90 | MAPK1 (0.33) | MAPK1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL15800467 | 0.85 | LMNA (0.34) | MAPK1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL10187594 | 0.84 | MAPK14 (0.33) | — | |
| SCHEMBL6727346 | 0.81 | HSD17B1 (0.34) | — | |
| SCHEMBL18874242 | 0.81 | HSD17B1 (0.34) | — | |
| SCHEMBL10196100 | 0.81 | MAOA (0.36) | — | |
| SCHEMBL19070977 | 0.81 | MAOA (0.36) | — | |
| SCHEMBL19071601 | 0.80 | ANPEP (0.34) | L3MBTL1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | MAPK1 2263/4885SMN1; SMN2 2952/4885LMNA 4657/4885 |
| US-20120094832-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | MAPK1 2045/4885SMN1; SMN2 2924/4885LMNA 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.