SCHEMBL1023029

SCHEMBL1023029

O=C(O)c1ccc(Nc2nc(Nc3ccc(C(=O)O)cc3)nc(Nc3ccc(C(=O)O)cc3)n2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.71
RAB9A P51151 3/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
AURKA O14965 3/20 0.64
RHOA P61586 1/20 0.62
AURKB Q96GD4 1/20 0.58
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ATM Q13315 1/20 0.54
GSK3B P49841 2/20 0.54
GSK3A P49840 1/20 0.54
GAA P10253 1/20 0.53
CAMK2D Q13557 2/20 0.53
PDE4B Q07343 2/20 0.52
PIN1 Q13526 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
MMP2 P08253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29874885 0.98 NPC1 (0.69) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL4569980 0.94 RHOA (0.72) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL5885121 0.91 NPC1 (0.61) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL304437 0.91 POLB (0.63) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL12998766 0.91 GAA (0.61) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL17212282 0.91 NPC1 (0.68) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL18516810 0.91 NPC1 (0.68) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL21925299 0.88 NPC1 (0.63) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL24390656 0.88 ALDH1A1 (0.63) NPC1RAB9ASMN1; SMN2AURKARHOA
SCHEMBL16687952 0.88 KMT2A (0.69) NPC1RAB9ASMN1; SMN2AURKARHOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037175-A Halogen-free flame-retardant transparent nylon and preparation method thereof 中化学科学技术研究有限公司 2026-05-15 CN claimed
EP-4673108-A1 SUNSCREEN COMPOSITIONS FOR PROTECTING SKIN MICROBIOME BASF SE (DE) 2026-01-07 EP claimed
EP-3695826-B1 USE OF SODA-LIME-BOROSILICATE IN A COSMETIC COMPOSITION TO REDUCE ADHESION OF SAND ON THE SKIN BEIERSDORF AG (DE) 2025-10-29 EP claimed
CN-119455908-A Chitosan-metal organic framework composite material and preparation and application thereof 北京大学 2025-02-18 CN claimed
CN-118681601-B ZrCu-MOG material for cascade degradation of organophosphorus nerve agents and preparation method and application thereof 重庆师范大学 2025-01-24 CN claimed
CN-118995030-A Flame-retardant waterborne polyurethane coating and preparation method and application thereof 北京宇阳泽丽防水材料有限责任公司 2024-11-22 CN claimed
CN-118681601-A ZrCu-MOG material for cascade degradation of organophosphorus nerve agents and preparation method and application thereof 重庆师范大学 2024-09-24 CN claimed
WO-2024180132-A1 SUNSCREEN COMPOSITIONS FOR PROTECTING SKIN MICROBIOME BASF SE (DE) 2024-09-06 WO claimed
CN-118085486-A Type II porous liquid containing high-concentration coordination cage and preparation method and application thereof 南京工业大学 2024-05-28 CN claimed
EP-3030214-B2 ALCOHOLIC SUNSCREEN GEL BEIERSDORF AG (DE) 2024-01-17 EP claimed
EP-0826360-B1 Use of dibenzoyl methane derivatives to attain or improve the solubility of triazine derivatives in oils BEIERSDORF AG (DE) 2004-06-02 EP claimed
EP-0786246-B1 Cosmetic and dermatological sunscreen formulations containing triazine derivatives and polyglyceryl-2-polyhydroxystearate BEIERSDORF AG (DE) 2004-06-02 EP claimed
EP-1100452-B1 COSMETIC OR DERMATOLOGICAL WATER/OIL EMULSIONS CONTAINING NONIONIC SURFACTANTS AND CHARACTERIZED BY A SILICONE EMULSIFYING AGENT CONTENT BEIERSDORF AG (DE) 2003-10-15 EP claimed
EP-0803244-B1 Use of mono- and diesters of branched alkanecarboxylic acids and diglycerine or triglycerine for the solubilsation of triazine derivatives in cosmetic and dermatological photoprotective compositions BEIERSDORF AG (DE) 2003-07-09 EP claimed
EP-0882445-B1 Cosmetic and dermatologic photoprotective formulation containing triazine derivates and mono-di-and/or trialkylesters of phosphonic acid BEIERSDORF AG (DE) 2002-12-11 EP claimed
EP-1076552-B1 COSMETIC AND DERMATOLOGICAL LIGHT-PROTECTIVE FORMULATIONS CONTAINING TRIAZINE DERIVATIVES AND ONE OR SEVERAL ESTERS OF UNBRANCHED-CHAIN CARBOXYLIC ACIDS AND BRANCHED-CHAIN ALCOHOLS BEIERSDORF AG (DE) 2002-07-17 EP claimed
EP-0876136-B1 STABLE COSMETIC AND DERMATOLOGICAL LIGHT-PROTECTING PREPARATIONS IN THE FORM OF WATER/OIL EMULSIONS CONTAINING INORGANIC MICRO-PIGMENTS, DERIVATIVES OF TRIAZINE AND/OR OTHER COMPONENTS BEIERSDORF AG (DE) 2002-05-08 EP claimed
EP-0860164-B1 Cosmetic and dermatological composition for sun protection containing triazine derivates and butylenglycol diesters BEIERSDORF AG (DE) 2001-12-12 EP claimed
US-5665334-A ULTRAVIOLET RADIATION 3V INC. (US) 1997-09-09 US claimed
EP-0779287-A1 Benzofuran derivatives and methods for their use as stabilizers and sunscreens against UV radiations 3V SIGMA S.p.A (IT) 1997-06-18 EP claimed