Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOA | P61586 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 4/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 5/20 | 0.61 |
| ▸ | GSK3A | P49840 | 4/20 | 0.61 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023029 | 0.94 | NPC1 (0.71) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL29874885 | 0.92 | NPC1 (0.69) | RHOAAURKAAURKBNPC1RAB9A | |
| 4-Phenylamino Benzoic Acid SCHEMBL70190 | 0.86 | MAPK13 (0.72) | AURKAAURKBATMMAPTMEN1 | |
| SCHEMBL9479471 | 0.86 | MAPK13 (0.72) | AURKAAURKBATMMAPTMEN1 | |
| SCHEMBL12998766 | 0.85 | GAA (0.61) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL17212282 | 0.85 | NPC1 (0.68) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL5885121 | 0.85 | NPC1 (0.61) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL304437 | 0.85 | POLB (0.63) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL18516810 | 0.85 | NPC1 (0.68) | RHOAAURKAAURKBNPC1RAB9A | |
| SCHEMBL11758273 | 0.84 | RHOA (0.54) | RHOAAURKAAURKBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8226761-B2 | Self-dispersed pigments and methods for making and using the same | SENSIENT COLORS LLC (US) | 2012-07-24 | — | — | US | disclosed |
| US-20120118205-A1 | SELF-DISPERSED PIGMENTS AND METHODS FOR MAKING AND USING THE SAME | SENSIENT COLORS INC. | 2012-05-17 | — | — | US | disclosed |
| US-8118924-B2 | Self-dispersed pigments and methods for making and using the same | SENSIENT COLORS LLC (US) | 2012-02-21 | — | — | US | disclosed |