SCHEMBL1023085

SCHEMBL1023085

O=S(O)c1ccccc1.[KH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
EPHX1 P07099 2/20 0.37
EPHX2 P34913 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
TSHR P16473 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
ALOX15 P16050 1/20 0.35
G6PD P11413 1/20 0.35
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10663817 0.97 HPGD (0.43) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL9175 0.97
SCHEMBL16674608 0.97
SCHEMBL49328 0.97
SCHEMBL1022859 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL1021742 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL64469 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL3151436 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL11298939 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2
SCHEMBL7969703 0.94 HPGD (0.41) HPGDEPHX1EPHX2ALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10835453-B2 Storage-stable resin-modified glass ionomer cement VOCO GMBH (DE) 2020-11-17 US claimed
EP-3338756-B1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2020-02-26 EP claimed
CN-109498464-A A kind of self-curing two-component adhesive composite, preparation method and application for dentistry inlay 吉林省登泰克牙科材料有限公司 2019-03-22 CN claimed
CN-109453037-A A kind of non-mixing type composition, preparation method and application for dental orthodontic bonding 吉林省登泰克牙科材料有限公司 2019-03-12 CN claimed
US-20180168938-A1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2018-06-21 US claimed
CN-1208316-C Process for producing retinol and intermediate compound for producing retinol SUMITOMO CHEMICAL CO (JP) 2005-06-29 CN claimed
EP-1199303-B1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL CO (JP) 2004-09-22 EP claimed
US-6660888-B2 A disulfone compound of given formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-09 US claimed
CN-1399535-A Dental Composition KERR CORP (US) 2003-02-26 CN claimed
CN-1356317-A Process for producing retinol and intermediate compound for producing retinol SUMITOMO CHEMICAL CO (JP) 2002-07-03 CN claimed
US-20020058844-A1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-16 US claimed
EP-1199303-A1 Process for producing retinol and intermediate compounds for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-24 EP claimed
US-6353041-B1 PLASTICS FOR SEALING ROOTS OF TEETH KERR CORPORATION 2002-03-05 US claimed
US-5621084-A Process for removal of allyl group or allyloxycarbonyl group PFIZER INC. (US) 1997-04-15 US claimed
EP-0676236-A1 Process for removal of allyl group or allyloxycarbonyl group PFIZER INC. (US) 1995-10-11 EP claimed
US-4110270-A ALKALI METAL SALT OF TOLUENE- OR BENZENE-SULFINIC ACID AS CATALYST BASF WYANDOTTE CORPORATION (US) 1978-08-29 US claimed
US-4039334-A ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US claimed
JP-9188513-A None JP disclosed
US-4110270-A ALKALI METAL SALT OF TOLUENE- OR BENZENE-SULFINIC ACID AS CATALYST BASF WYANDOTTE CORPORATION (US) 1978-08-29 US disclosed
US-4039334-A ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058844-A1 Process for producing retinol and intermediate compounds for producing the same ADH4, ADH1B, ADH7 HPGD 364/4885EPHX1 676/4885EPHX2 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.