Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360484 | 0.76 | ALOX15 (0.35) | KDM4ENPSR1ALDH1A1MAPTALOX15 | |
| SCHEMBL13328153 | 0.76 | ALOX15 (0.35) | KDM4ENPSR1ALDH1A1MAPTALOX15 | |
| SCHEMBL15031976 | 0.75 | ALDH1A1 (0.40) | RAB9AKDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL22313333 | 0.75 | ADORA1 (0.39) | — | |
| SCHEMBL18117472 | 0.73 | KDM4E (0.38) | RAB9AKDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL13030214 | 0.73 | HSD17B10 (0.36) | KDM4EALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL13360470 | 0.73 | HSD17B10 (0.36) | KDM4ENPSR1ALDH1A1MAPTALOX15 | |
| SCHEMBL1143872 | 0.72 | ALDH1A1 (0.49) | RAB9AKDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL18117485 | 0.71 | ALDH1A1 (0.37) | RAB9AKDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL13328146 | 0.69 | ALOX15 (0.33) | KDM4EALDH1A1MAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771450-B9 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION BY INHIBITION OF AURORA KINASE | MILLENNIUM PHARM INC (US) | 2008-12-24 | — | — | EP | disclosed |