Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117485 | 0.96 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL21603883 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL18117472 | 0.81 | KDM4E (0.38) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL21603780 | 0.80 | MEN1 (0.41) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL1143872 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL13569707 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL10239408 | 0.75 | RAB9A (0.35) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL22789230 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL22789273 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4EALOX15HSD17B10 | |
| SCHEMBL2096219 | 0.72 | CYP1A2 (0.38) | ALDH1A1MAPTKDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150399-A1 | INHIBITORS OF THE UNFOLDED PROTEIN RESPONSE AND METHODS FOR THEIR USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150399-A1 | INHIBITORS OF THE UNFOLDED PROTEIN RESPONSE AND METHODS FOR THEIR USE | XBP1, HSPA5, RNASE1 | ALDH1A1 4357/4885MAPT 2111/4885KDM4E 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.