SCHEMBL1024107

SCHEMBL1024107

CC(C)(C)c1ccc(N)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.69
ALDH1A1 P00352 3/20 0.69
MEN1 O00255 2/20 0.69
GAA P10253 2/20 0.69
KMT2A Q03164 2/20 0.69
PKM P14618 1/20 0.69
RECQL P46063 1/20 0.69
ALOX15 P16050 2/20 0.64
HSD17B10 Q99714 2/20 0.64
HPGD P15428 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
CYP3A4 P08684 1/20 0.50
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
POLB P06746 2/20 0.45
RAB9A P51151 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP2D6 P10635 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412591 0.86 ESR1 (0.56) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL565076 0.86 ESR1 (0.56) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL29397448 0.86 ESR1 (0.56) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL23155928 0.83 ALDH1A1 (0.48) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL621595 0.82 ALDH1A1 (1.00) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL8515161 0.79 ALDH1A1 (0.66) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL3278920 0.79 ESR1 (0.50) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL564979 0.79 ESR1 (0.48) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL564039 0.79 ESR1 (0.61) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL256203 0.78 ALDH1A1 (0.64) MAPTALDH1A1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431422-A Boron-nitrogen-containing compound and application thereof 阜阳欣奕华新材料科技股份有限公司 2025-02-14 CN disclosed
US-9897915-B2 Photosensitive resin composition, method for producing heat-resistant resin film and display device TORAY INDUSTRIES, INC. (JP) 2018-02-20 US disclosed
US-9897915-B2 Photosensitive resin composition, method for producing heat-resistant resin film and display device TORAY INDUSTRIES, INC. (JP) 2018-02-20 US disclosed
EP-2274983-B1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-05-31 EP disclosed
EP-2274983-B1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-05-31 EP disclosed
US-20150301453-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING HEAT-RESISTANT RESIN FILM AND DISPLAY DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-22 US disclosed
US-20150301453-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING HEAT-RESISTANT RESIN FILM AND DISPLAY DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-22 US disclosed
US-8642604-B2 Substituted pyrazolo[3,2-d]pyrimidines as anti-cancer agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-02-04 US disclosed
US-8609705-B2 Fused heterocyclic compounds, and compositions thereof, for use in arthropod pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-17 US disclosed
CN-102006776-B Harmful arthropod control composition, and fused heterocyclic compound SUMITOMO CHEMICAL CO 2013-09-25 CN disclosed
US-20090240011-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PHOSPHINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-09-24 US disclosed
US-7585868-B2 Substituted pyrazolo[3,4-D]pyrimidines as kinase antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-09-08 US disclosed
EP-1994040-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PHOSPHINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-11-26 EP disclosed
EP-1303483-B1 NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PACIFIC CORP (KR) 2008-04-23 EP disclosed
US-20070293516-A1 Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-12-20 US disclosed
WO-2007104679-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PHOSPHINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-09-20 WO disclosed
EP-1832597-A1 Polymerisation of ethylene and alpha-olefins with phosphino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-09-12 EP disclosed
US-4620010-A Process for preparing carboalkoxy substituted benzoxazole compounds USV PHARMACEUTICAL CORP. (US) 1986-10-28 US disclosed
US-4367235-A CARDIOVASCULAR DISORDERS BOEHRINGER MANNHEIM GMBH (DE) 1983-01-04 US disclosed
EP-0000784-A1 4-Hydroxy-2-benzimidazolinone derivatives, process for their preparation and their use in medicaments Roche Diagnostics GmbH (DE) 1979-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293516-A1 Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine MTOR, PI4KA, PIK3CA MAPT 3686/4885ALDH1A1 4725/4885MEN1 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.