SCHEMBL564979

SCHEMBL564979

CC(C)(c1ccc(N)cc1)c1ccc(N)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.48
ESR2 Q92731 4/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 3/20 0.45
CYP3A4 P08684 3/20 0.45
HPGD P15428 3/20 0.45
AR P10275 2/20 0.45
TSHR P16473 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
HTR6 P50406 1/20 0.45
ESRRG P62508 1/20 0.45
SLC6A3 Q01959 1/20 0.45
ALOX15 P16050 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397448 0.92 ESR1 (0.56) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL29412591 0.92 ESR1 (0.56) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL565076 0.92 ESR1 (0.56) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL564039 0.89 ESR1 (0.61) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL565312 0.87 ESR1 (0.57) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL565140 0.85 ALDH1A1 (0.66) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL8515161 0.85 ALDH1A1 (0.66) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL564555 0.84 ESR1 (0.50) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL20869793 0.82 ALDH1A1 (0.41) ESR1ESR2ALDH1A1MAPTMEN1
SCHEMBL11131754 0.81 ESR1 (0.77) ESR1ESR2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ESR1 1065/4885ESR2 1253/4885ALDH1A1 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.