Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926740 | 0.90 | MET (0.55) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL13115581 | 0.87 | NPC1 (0.66) | ALDH1A1MAPTLMNARAB9AKMT2A | |
| SCHEMBL4075316 | 0.86 | MEN1 (0.61) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL23136505 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL14096629 | 0.81 | RAB9A (0.69) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL4401153 | 0.81 | RAB9A (0.73) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL25130188 | 0.81 | MEN1 (0.71) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL4074446 | 0.76 | MET (0.56) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL1871517 | 0.76 | RAB9A (0.69) | ALDH1A1MAPTGAALMNARAB9A | |
| SCHEMBL14096626 | 0.75 | RAB9A (1.00) | ALDH1A1MAPTLMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409704-A2 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2012-01-25 | — | — | EP | disclosed |