SCHEMBL10243380

SCHEMBL10243380

COC(=O)NCCNS(=O)(=O)c1ccccc1OC

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ITGAV P06756 2/20 0.51
FABP4 P15090 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
KAT6A Q92794 1/20 0.46
ALDH1A1 P00352 1/20 0.46
USP2 O75604 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 1/20 0.44
PKM P14618 1/20 0.44
NAMPT P43490 1/20 0.44
KDM4E B2RXH2 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
HTR6 P50406 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7486079 0.82 SMN1; SMN2 (0.50) ITGAVFABP4SMN1; SMN2MAPTKAT6A
SCHEMBL15467870 0.82 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1USP2POLBL3MBTL1
SCHEMBL3203408 0.81 FABP4 (0.60) ITGAVFABP4SMN1; SMN2MAPTKAT6A
SCHEMBL3564486 0.80 L3MBTL1 (0.64) SMN1; SMN2ALDH1A1USP2HSD17B10POLB
SCHEMBL2676737 0.79 FABP4 (0.67) FABP4ALDH1A1L3MBTL1CA12CA9
SCHEMBL7552123 0.79 KAT6A (0.52) ITGAVKAT6APKMNAMPTHTR6
SCHEMBL4183041 0.78 MAPT (0.68) ITGAVFABP4SMN1; SMN2MAPTKAT6A
SCHEMBL4617734 0.78 ALDH1A1 (0.63) FABP4SMN1; SMN2ALDH1A1USP2HSD17B10
Hydrochloric Acid SCHEMBL27202572 0.78 CYP3A4 (0.51) SMN1; SMN2KAT6AALDH1A1USP2HSD17B10
SCHEMBL29695202 0.77 FABP4 (0.61) FABP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 ITGAV 4233/4885FABP4 4456/4885SMN1; SMN2 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.