Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282622 | 0.88 | CKS1B (0.46) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL12747338 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL15617812 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL10243447 | 0.80 | APP (0.54) | KDM4EGAA | |
| SCHEMBL12338697 | 0.79 | TDP1 (0.78) | SMN1; SMN2MAPTLIN28ATDP1TRPM8 | |
| SCHEMBL10243173 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP2D6 | |
| SCHEMBL28305760 | 0.78 | TDP1 (0.57) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL19877250 | 0.78 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL8285006 | 0.78 | RAB9A (0.57) | ALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL10243111 | 0.77 | POLB (0.46) | ALDH1A1MAPTTDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | ALDH1A1 1939/4885SMN1; SMN2 3120/4885MAPT 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.