SCHEMBL10244094

SCHEMBL10244094

CCN(CCNC(=O)OC)C(C)c1ccc(N2CCC(O)CC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.43
ACACB O00763 17/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10244305 0.87 ALDH1A1 (0.42) RORCACACB
SCHEMBL10243906 0.87 HDAC3 (0.44) RORCACACB
SCHEMBL10243779 0.79 ACACB (0.44) RORCACACB
SCHEMBL10243510 0.78 ALOX5 (0.40)
SCHEMBL10282510 0.78 ACACB (0.39) RORCACACB
SCHEMBL10244535 0.78 KMT2A (0.37) ACACB
SCHEMBL10244079 0.77 ALDH1A1 (0.40)
SCHEMBL10243433 0.77 MAPT (0.43)
SCHEMBL10244037 0.77 CYP1A2 (0.46)
SCHEMBL10243491 0.77 MEN1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 RORC 80/4885ACACB 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.