⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996315 | 0.85 | EPHX1 (0.57) | — | |
| SCHEMBL13079149 | 0.84 | EPHX1 (0.60) | — | |
| SCHEMBL9194193 | 0.81 | KMT2A (0.47) | — | |
| SCHEMBL1304101 | 0.79 | TDP1 (0.53) | — | |
| SCHEMBL294319 | 0.79 | — | — | |
| SCHEMBL7521952 | 0.78 | — | — | |
| SCHEMBL6892765 | 0.78 | ACHE (0.53) | — | |
| SCHEMBL6446718 | 0.78 | CTSS (0.32) | — | |
| SCHEMBL13258949 | 0.77 | — | — | |
| SCHEMBL3190326 | 0.77 | EPHX1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |