Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | IDE | P14735 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024507 | 0.97 | HLCS (0.72) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL1075131 | 0.93 | HLCS (0.66) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL19514780 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5585656 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL10140211 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5585660 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL12424056 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL565406 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL33865 | 0.91 | TDP1 (0.71) | HLCSTDP1MEN1ABL1LMNA | |
| Biotin SCHEMBL27481190 | 0.90 | TDP1 (0.72) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077174-A1 | METHODS FOR CULTURING NR4A-DEFICIENT CELLS | LYELL IMMUNOPHARMA, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2023147185-A9 | METHODS FOR MAKING AND USING ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS TO ENHANCE T-CELL THERAPIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-01-04 | — | — | WO | disclosed |
| US-20230340404-A1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2023147185-A1 | METHODS FOR MAKING AND USING ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS TO ENHANCE T-CELL THERAPIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20230181644-A1 | METHODS OF GENERATING CELLS | LYELL IMMUNOPHARMA, INC. (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2023076511-A1 | METHODS OF GENERATING CELLS | LYELL IMMUNOPHARMA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| US-11555177-B2 | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-17 | — | — | US | disclosed |
| US-20190292517-A1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2019-09-26 | — | — | US | disclosed |
| EP-3484448-A1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | President and Fellows of Harvard College (US) | 2019-05-22 | — | — | EP | disclosed |
| WO-2018013797-A1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-01-18 | — | — | WO | disclosed |
| US-20020102216-A1 | Enhanced ultrasound detection with temperature-dependent contrast agents | KEREOS, INC. | 2002-08-01 | — | — | US | disclosed |
| US-20020052311-A1 | Methods and compostions for the treatment and/or diagnosis of neurological diseases and disorders | RAMOT, UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2002-05-02 | — | — | US | disclosed |
| EP-0831933-A4 | SITE SPECIFIC BINDING SYSTEM, IMAGING COMPOSITIONS AND METHODS | BARNES JEWISH HOSPITAL D B A (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000071172-A1 | SITE SPECIFIC BINDING SYSTEM, NUCLEAR IMAGING COMPOSITIONS AND METHODS | BARNES-JEWISH HOSPITAL (US) | 2000-11-30 | — | — | WO | disclosed |
| US-5989520-A | BIOTINYLATED LIPID COATED EMULSION CONTAINING A PARAMAGNETIC ELEMENT AND A FLUOROCHEMICAL | BARNES-JEWISH HOSPITAL (US) | 1999-11-23 | — | — | US | disclosed |
| US-5958371-A | COMPLEXING | BARNES-JEWISH HOSPITAL (US) | 1999-09-28 | — | — | US | disclosed |
| US-5780010-A | DRUG DELIVERY | BARNES-JEWISH HOSPITAL (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0831933-A1 | SITE SPECIFIC BINDING SYSTEM, IMAGING COMPOSITIONS AND METHODS | Barnes-Jewish Hospital D/B/A (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5690907-A | Avidin-biotin conjugated emulsions as a site specific binding system | THE JEWISH HOSPITAL OF ST. LOUIS (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1996041647-A1 | SITE SPECIFIC BINDING SYSTEM, IMAGING COMPOSITIONS AND METHODS | BARNES-JEWISH HOSPITAL D/B/A (US) | 1996-12-27 | — | — | WO | disclosed |