Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024050 | 0.89 | GABRR1 (0.36) | CPB2GSRGABRR1 | |
| SCHEMBL15238859 | 0.84 | CA2 (0.41) | — | |
| SCHEMBL15239244 | 0.84 | CA2 (0.41) | — | |
| SCHEMBL3726149 | 0.84 | ACACB (0.30) | — | |
| SCHEMBL18342420 | 0.82 | — | — | |
| SCHEMBL18342421 | 0.82 | — | — | |
| SCHEMBL16195856 | 0.81 | — | — | |
| SCHEMBL14908935 | 0.80 | CHRM1 (0.35) | — | |
| SCHEMBL14908934 | 0.80 | CHRM1 (0.35) | — | |
| SCHEMBL23833303 | 0.79 | ALOX15 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-B1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO KG (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AICURIS GMBH & CO. KG (DE) | 2008-12-11 | — | — | US | disclosed |
| US-7446102-B2 | Antibacterial amide macrocycles IV | AICURIS GMBH & CO. KG (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20080076745-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO. KG (DE) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076745-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | NOD2, AAAS, AADAC | CPB2 2025/4885GSR 833/4885RNPEP 648/4885 |
| US-20080306040-A1 | Antibacterial amide macrocycles VII | AADAC, AAAS, NOD2 | CPB2 1343/4885GSR 743/4885RNPEP 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.