SCHEMBL1024585

SCHEMBL1024585

COCCn1cnc2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 9/20 0.73
LMNA P02545 6/20 0.73
TDP1 Q9NUW8 1/20 0.70
L3MBTL1 Q9Y468 1/20 0.69
RAB9A P51151 3/20 0.61
GAA P10253 1/20 0.61
ALOX15 P16050 1/20 0.60
TSHR P16473 1/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HTT P42858 4/20 0.58
MAPT P10636 2/20 0.58
STAT3 P40763 1/20 0.58
LTA4H P09960 1/20 0.58
NPC1 O15118 2/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
PKM P14618 1/20 0.56
EGLN3 Q9H6Z9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14423493 0.91 SMN1; SMN2 (0.85) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL501944 0.91 SMN1; SMN2 (0.85) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL5374402 0.91 SMN1; SMN2 (0.85) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL92599 0.91 SMN1; SMN2 (0.85) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL741950 0.90 SMN1; SMN2 (0.66) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL502183 0.88 SMN1; SMN2 (0.75) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL501859 0.87 SMN1; SMN2 (0.74) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL352045 0.86 SMN1; SMN2 (0.96) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL351186 0.84 SMN1; SMN2 (1.00) SMN1; SMN2LMNATDP1L3MBTL1RAB9A
SCHEMBL29924240 0.84 SMN1; SMN2 (1.00) SMN1; SMN2LMNATDP1L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497382-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2025-12-16 US disclosed
EP-4605398-A1 BICYCLIC FERROPORTIN INHIBITORS Vifor (International) AG (CH) 2025-08-27 EP disclosed
WO-2024083980-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2024-04-25 WO disclosed
US-20230391747-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2023-12-07 US disclosed
EP-4271674-A1 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2023-11-08 EP disclosed
US-11702404-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2023-07-18 US disclosed
US-20230152692-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
WO-2022225914-A1 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-10-27 WO disclosed
CN-114630823-A GLP-1R modulating compounds 吉利德科学公司 2022-06-14 CN disclosed
US-11279681-B2 3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors VALO HEALTH, INC. (US) 2022-03-22 US disclosed
CN-102084535-B Dye-sensitized photoelectric conversion element PECCELL TECHNOLOGIES INC 2014-07-02 CN disclosed
WO-2013026563-A1 ADDITIVES FOR DYE-SENSITIZED SOLAR CELLS MERCK PATENT GMBH (DE) 2013-02-28 WO disclosed
WO-2013024119-A1 RUTHENIUM-BASED COMPLEX CATALYSTS THE GOVERNING COUNCIL OF UNIVERSITY OF TORONTO (CA) 2013-02-21 WO disclosed
CN-102084535-A Dye-sensitized photoelectric conversion element PECCELL TECHNOLOGIES INC 2011-06-01 CN disclosed
US-20110041915-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT PECCELL TECHNOLOGIES, INC. (JP) 2011-02-24 US disclosed
EP-2276103-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT Peccell Technologies Inc (JP) 2011-01-19 EP disclosed
US-7252925-B2 Nitrogen-containing organic compound, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-07 US disclosed
US-7252925-B2 Nitrogen-containing organic compound, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-07 US disclosed
US-7252925-B2 Nitrogen-containing organic compound, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-07 US disclosed
US-20050095533-A1 Nitrogen-containing organic compound, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279681-B2 3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors HDAC1, HDAC4, HDAC2 SMN1; SMN2 1067/4885LMNA 1023/4885TDP1 666/4885
US-11702404-B2 GLP-1R modulating compounds GLP1R, GIPR, GPR119 SMN1; SMN2 1956/4885LMNA 3309/4885TDP1 3351/4885
US-20230391747-A1 GLP-1R MODULATING COMPOUNDS GLP1R, GIPR, GPR119 SMN1; SMN2 1956/4885LMNA 3309/4885TDP1 3351/4885
US-12497382-B2 GLP-1R modulating compounds GLP1R, GIPR, GPR119 SMN1; SMN2 1956/4885LMNA 3309/4885TDP1 3351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.