Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 12/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126801 | 0.92 | CHRM5 (0.46) | CXCR4SIGMAR1CHRM5CHRM3 | |
| SCHEMBL28170665 | 0.83 | CXCR4 (0.50) | CXCR4SIGMAR1CHRM5CHRM3MEN1 | |
| SCHEMBL6826228 | 0.82 | SIGMAR1 (0.48) | CXCR4SIGMAR1CHRM5CHRM3MEN1 | |
| SCHEMBL8732181 | 0.80 | — | — | |
| SCHEMBL10248697 | 0.80 | — | — | |
| SCHEMBL12226505 | 0.80 | CHRM5 (0.53) | CXCR4SIGMAR1CHRM5CHRM3MEN1 | |
| SCHEMBL10283313 | 0.80 | ALDH1A1 (0.58) | CXCR4SIGMAR1CHRM5CHRM3MEN1 | |
| SCHEMBL9059440 | 0.79 | — | — | |
| SCHEMBL10246527 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2ATDP1HRH3 | |
| SCHEMBL10248708 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2ATDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | FRONTIER SCIENTIFIC, INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | BLVRB, BTD, BCL6B | CXCR4 1349/4885SIGMAR1 4074/4885CHRM5 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.