SCHEMBL10246766

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11382394	0.86	ALOX5 (0.49)	TSHRALDH1A1HSD17B10GABRPGABRD
	SCHEMBL3170947	0.86	CSF1R (0.43)	TSHRALDH1A1HSD17B10KDM4ERAB9A
	SCHEMBL401738	0.83	PDK2 (0.46)	TSHRALDH1A1HSD17B10GABRPGABRD
	SCHEMBL6502372	0.83	TSHR (0.53)	TSHRALDH1A1HSD17B10KDM4ERAB9A
	SCHEMBL3181692	0.81	MYC (0.47)	TSHRALDH1A1HSD17B10KDM4ERAB9A
	SCHEMBL10191565	0.81	CSF1R (0.42)	TSHRALDH1A1HSD17B10KDM4ERAB9A
	SCHEMBL5771735	0.81	ALDH1A1 (0.50)	TSHRALDH1A1HSD17B10KDM4ERAB9A
	SCHEMBL22886783	0.79	MGAM (0.49)	TSHRTDP2ALDH1A1HSD17B10GABRP
	SCHEMBL5773388	0.77	TARBP2 (0.48)	TSHRALDH1A1GABRA2GABRB2KDM4E
	SCHEMBL5771407	0.76	TSHR (0.47)	TSHRALDH1A1HSD17B10KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.