Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255985 | 0.85 | KDM4E (0.45) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL10247154 | 0.80 | KDM4E (0.67) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL174661 | 0.78 | HSD17B10 (0.66) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL255430 | 0.75 | HSD17B10 (0.53) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL10246929 | 0.71 | HSD17B10 (0.54) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL255810 | 0.69 | HSD17B10 (0.64) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL173910 | 0.68 | ALDH1A1 (0.51) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL6779223 | 0.66 | CDC7 (0.61) | KDM4EALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL10246838 | 0.66 | HSD17B10 (0.67) | HSD17B10KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL255764 | 0.66 | KDM4E (0.43) | HSD17B10KDM4ERAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | HSD17B10 2001/4885KDM4E 2988/4885RAB9A 314/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | HSD17B10 733/4885KDM4E 2511/4885RAB9A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.