Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042620 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4EPOLQTDP1LIMK1 | |
| SCHEMBL25618858 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10ALOX15POLQ | |
| SCHEMBL3433340 | 0.69 | AOC1 (0.47) | ALDH1A1KDM4EHSD17B10ALOX15POLB | |
| SCHEMBL163040 | 0.69 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL6779532 | 0.68 | GAA (0.59) | ALDH1A1KDM4EHPGDPOLBPOLQ | |
| Hydrochloric Acid SCHEMBL1964472 | 0.67 | AOC1 (0.49) | ALDH1A1KDM4EHSD17B10ALOX15POLB | |
| SCHEMBL174140 | 0.67 | RAB9A (0.65) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL5591777 | 0.67 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL9656308 | 0.66 | HSD11B1 (0.47) | ALDH1A1KDM4EHPGDPOLBTDP1 | |
| SCHEMBL173609 | 0.66 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103188936-B | Insecticidal composition | DOW AGROSCIENCES LLC (US) | 2016-04-20 | — | — | CN | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-8604211-B2 | Pesticidal compositions | Dow AroSciecnes, LLC. (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| CN-103188936-A | Insecticidal composition | DOW AGROSCIENCES LLC | 2013-07-03 | — | — | CN | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ALDH1A1 1882/4885KDM4E 2988/4885HSD17B10 2001/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ALDH1A1 1438/4885KDM4E 2511/4885HSD17B10 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.