Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 15/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255640 | 0.86 | HSD17B10 (0.47) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL255642 | 0.86 | HSD17B10 (0.47) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL173467 | 0.86 | HSD17B10 (0.64) | KDM4EHSD17B10RAB9AALDH1A1TSHR | |
| SCHEMBL255431 | 0.85 | KDM4E (0.69) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL10246903 | 0.85 | KDM4E (0.46) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL255154 | 0.85 | KDM4E (0.46) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL255430 | 0.81 | HSD17B10 (0.53) | KDM4EHSD17B10RAB9AALDH1A1TP53 | |
| SCHEMBL255827 | 0.79 | HSD17B10 (0.61) | KDM4EHSD17B10RAB9AALDH1A1TSHR | |
| SCHEMBL13047525 | 0.78 | LMNA (0.33) | HSD17B10ALDH1A1CYP1A2LMNACYP3A4 | |
| SCHEMBL13048852 | 0.77 | ALOX5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 2988/4885HSD17B10 2001/4885RAB9A 314/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 2511/4885HSD17B10 733/4885RAB9A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.