Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018753 | 0.83 | SLC6A3 (0.43) | SLC6A3DRD2HTR2AHRH1CACNA1G | |
| SCHEMBL10249190 | 0.83 | SLC6A3 (0.56) | SLC6A3DRD2HTR2AHRH1SMN1; SMN2 | |
| SCHEMBL13604293 | 0.81 | CYP17A1 (0.44) | SLC6A3DRD2HTR2AHRH1SMN1; SMN2 | |
| SCHEMBL10252493 | 0.81 | LTA4H (0.48) | SLC6A3SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL10252529 | 0.80 | LTA4H (0.47) | SLC6A3DRD2HTR2AHRH1ALDH1A1 | |
| SCHEMBL10248949 | 0.80 | LOXL2 (0.42) | SLC6A3DRD2HTR2AHRH1PTPRB | |
| SCHEMBL10284918 | 0.79 | SMN1; SMN2 (0.55) | SLC6A3GFERHSP90AB1HTR2ASMN1; SMN2 | |
| SCHEMBL10248870 | 0.78 | SLC6A3 (0.43) | SLC6A3DRD2HTR2AHRH1ALDH1A1 | |
| SCHEMBL623682 | 0.76 | NPC1 (0.59) | GFERHSP90AB1MAPTALDH1A1NPC1 | |
| SCHEMBL16018768 | 0.75 | SLC6A3 (0.40) | SLC6A3DRD2HTR2AHRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | TRPV1, SCN1A, SCN2A | SLC6A3 227/4885GFER 976/4885HSP90AB1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.