SCHEMBL10249527

SCHEMBL10249527

Cc1ccccc1C[Si](C)(C)O[Si](C)(O[Si](C)(C)CC[Si](C)(C)O[Si](C)(C)C)O[Si](C)(C)Cc1ccccc1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32
MAOB P27338 1/20 0.32
CYP2A13 Q16696 1/20 0.32
SGMS2 Q8NHU3 1/20 0.32
HPGD P15428 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CTBP2 P56545 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
KMT2A Q03164 1/20 0.31
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31
CHRM2 P08172 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10249514 0.82 TAAR1 (0.43) TAAR1ADRA2AADRA2BADRA2CPOLB
SCHEMBL8759213 0.80 TAAR1 (0.47) TAAR1ADRA2AADRA2BADRA2CPOLB
SCHEMBL14212742 0.77 TAAR1 (0.44) TAAR1ADRA2AADRA2BADRA2CPOLB
SCHEMBL10249516 0.74
SCHEMBL14106722 0.72 MTNR1A (0.41) POLBNPC1HPGDALDH1A1KMT2A
SCHEMBL8759222 0.72 TAAR1 (0.50) TAAR1ADRA2AADRA2BADRA2CPOLB
SCHEMBL17753758 0.71 MPO (0.40) TAAR1
SCHEMBL15799891 0.71 IDO1 (0.42) TAAR1ALDH1A1KMT2ACHRM2
SCHEMBL23906944 0.70 TAAR1 (0.38) TAAR1ADRA2AADRA2BADRA2CCDK4
SCHEMBL12445406 0.69 IDO1 (0.52) TAAR1ALDH1A1KMT2ACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188887-B2 Polycarbonate copolymer, coating fluid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer IDEMITSU KOSAN CO., LTD. (JP) 2015-11-17 US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed