SCHEMBL10249537

SCHEMBL10249537

CCCC[Si](C)(C)O[Si](C)(C)Cc1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.38
KCNH2 Q12809 4/20 0.36
AGXT P21549 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
IDO1 P14902 1/20 0.32
CNR2 P34972 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GFER P55789 1/20 0.32
ATM Q13315 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10249585 0.86 NPC1 (0.40) HPGDKCNH2ALDH1A1CNR2NPC1
SCHEMBL10249515 0.85 AGXT (0.43) KCNH2AGXTALDH1A1IDO1CYP1A2
SCHEMBL16749887 0.81 CNR2 (0.35) HPGDKCNH2CNR2SMN1; SMN2CYP1A2
SCHEMBL11200 0.74 TSHR (0.35) TSHR
SCHEMBL9231420 0.74 CYP1A2 (0.46) KCNH2AGXTALDH1A1MEN1KMT2A
SCHEMBL17225128 0.73 AGXT (0.41) AGXTALDH1A1KMT2AIDO1NPC1
SCHEMBL10584058 0.73 ACHE (0.37) HPGDMEN1KMT2ANPC1RAB9A
SCHEMBL10249522 0.72 SMN1; SMN2 (0.34) HPGDMEN1KMT2ACNR2NPC1
SCHEMBL17791455 0.71 AGXT (0.39) KCNH2AGXTALDH1A1IDO1NPC1
SCHEMBL13789624 0.71 CYP1A2 (0.41) KCNH2AGXTIDO1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9389524-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photoreceptor IDEMITSU KOSAN CO., LTD. (JP) 2016-07-12 US disclosed
US-9188887-B2 Polycarbonate copolymer, coating fluid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer IDEMITSU KOSAN CO., LTD. (JP) 2015-11-17 US disclosed
US-20150147689-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR IDEMITSU KOSAN CO., LTD. (JP) 2015-05-28 US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed